Tamarind Seed Xyloglucans Promote Proliferation and Migration of Human Skin Cells through Internalization via Stimulation of Proproliferative Signal Transduction Pathways

Figure 2

BrdU incorporation as marker for cell proliferation. NHEK (a), HaCaT (b), and NHDF (c) were incubated with TSw and TSc in concentrations of 0.01–100 µg/mL for 48 h. Mean values ± SD of 𝑛=8 replicates of three independent experiments are shown with ^∗𝑃<0.05 and ^∗∗𝑃<0.01 compared to untreated cells as well as with ⁺⁺𝑃<0.01 compared to cells treated with 0.01 µg/mL and 10 µg/mL TSc; 10% FCS = positive control. Results were normalized to untreated cells (=100%, black line).

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(b)

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