IL-1RN VNTR Polymorphism in Adult Dermatomyositis and Systemic Lupus Erythematosus
Table 3
Comparison between the genotypes and the ACR criteria for SLE.
Genotype
1/1 ()
1/2 ()
2/2 ()
1/3 ()
3/3 ()
value
Malar rash
28 (68.3%)
4 (50.0%)
2 (50.0%)
0 (0.0%)
0 (0.0%)
NS*
Discoid rash
7 (17.1%)
3 (37.5%)
1 (25.0%)
0 (0.0%)
0 (0.0%)
NS
Photosensitivity
23 (57.1%)
5 (61.5%)
2 (50.0%)
1 (100.0%)
0 (0.0%)
NS
Oral ulcer
3 (7.3%)
1 (12.5%)
0 (0.0%)
0 (0.0%)
0 (0.0%)
NS
Arthritis
29 (70.7%)
5 (62.5%)
2 (50.0%)
0 (0.0%)
1 (100.0%)
NS
Serositis
10 (24.4%)
1 (12.5%)
0 (0.0%)
0 (0.0%)
0 (0.0%)
NS
Renal disease
41 (100.0%)
8 (100.0%)
4 (100.0%)
1 (100.0%)
1 (100.0%)
NS
Neurological disease
10 (22.9%)
1 (12.5%)
0 (0.0%)
0 (0.0%)
1 (100.0%)
NS
Haematological disease
15 (36.6%)
4 (50.0%)
1 (25.0%)
0 (0.0%)
0 (0.0%)
NS
Immunological disease
24 (58.3%)
5 (62.5%)
3 (75.0%)
1 (100.0%)
1 (100.0%)
NS
(Anti-dsDNA, anti-Sm, anti-phospholipid Ab)
ANA
29 (70.7%)
7 (87.5%)
2 (50.0%)
0 (0.0%)
1 (100.0%)
NS
*Not significant, anti-dsDNA: antibodies to the double stranded DNA, anti-SM: anti-Smith antibodies (specific markers for SLE), and ANA: antinuclear antibodies.
