Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders

Table 2

Summary of genetic differences between hereditary reticulate pigmentary disorders.

Disorder	DSH	DUH	RAPK	DPR	NFJS	EBS-MP	ACD
Mode of inheritance	AD	AD	AD	AD	AD	AD	AR
Gene mutation	ADAR1	ABCB6	ADAM10	KRT14	KRT14	KRT5	Unknown
Chromosome location	1q21.3	2q35	15q21.3	17q11.2–q21	17q11.2–q21	12q13.13	Unknown

AD: autosomal dominant; AR: autosomal recessive; DSH: dyschromatosis symmetrica hereditaria; DUH: dyschromatosis universalis hereditaria; RAPK: reticulate acropigmentation of Kitamura; DPR: dermatopathia pigmentosa reticularis; NFJS: Naegeli-Franceschetti-Jadassohn Syndrome; EBS-MP: epidermolysis bullosa simplex with mottled pigmentation; ACD: amyloidosis cutis dyschromica.