Research Article

Clinical and Physiological Correlates of Irritability in Depression: Results from the Netherlands Study of Depression and Anxiety

Table 2

Demographic and clinical characteristics of low and high irritable depressed patients—multivariate resultsa.

Low irritable
( )
High irritable
( )

Age of onset (mean ± SD)29.0 ± 13.226.9 ± 12.4
Beck Anxiety Inventory (mean ± SD)16.6 ± 9.523.9 ± 11.3 **
LEIDS (mean ± SD)
 Aggression5.0 ± 4.28.8 ± 5.1 ***
NEO FFI (mean ± SD)
 Neuroticism41.2 ± 6.845.3 ± 6.1 *
 Openness31.1 ± 5.130.6 ± 5.9
 Agreeableness44.0 ± 5.041.4 ± 5.6 ***

 *.085 < P >  .05.
**.05 < P >  .001.
*** P <  .001.
aControlled for current symptoms (IDS-total minus item 6), gender, and age.