Research Article

Efficacy of Chronic Antidepressant Treatments in a New Model of Extreme Anxiety in Rats

Table 3

Effects of acute diazepam (DZP) treatment (1 mg/kg, IP, , median with limits of interquartile range values). Wilcoxon-test: # (test versus baseline). Data were expressed as median with limits of interquartile range values.

MeasuresBaseline (before treatment)Test (after treatment)
Vehicle ( )DZP ( )Vehicle ( )DZP ( )

Number of jumps20 (15.5–23.5)21 (15.3–28.8)21 (17.5–23.3)16 (12.3–22.3)
Latency before the first jump (s)17 (9.8–21.8)15 (10.8–20.8)13 (9.8–15.5)21 (14.0–23.3)
Immobility (s)106 (61.5–125.5)101 (80.3–129.8)121# (104.0–141.3)90 (75.0–103.0)