Depression Research and Treatment / 2011 / Article / Tab 5

Research Article

Efficacy of Chronic Antidepressant Treatments in a New Model of Extreme Anxiety in Rats

Table 5

Effects of acute clonazepam (CZP) treatment (1 mg/kg, IP, , median with limits of interquartile range values). Mann-Whitney U test: * ; ** (CZP versus vehicle). Wilcoxon-test: # ; ## (test versus baseline). Data were expressed as median with limits of interquartile range values.

MeasuresBaseline (before treatment)Test (after treatment)
Vehicle ( )CZP ( )Vehicle ( )CZP ( )

Number of jumps17 (9.75–21.75)15 (11–17)18 (15.25–20.5)3**## (2–8)
Latency before the first jump (s)14 (6.5–35.75)12 (4.5–19.5)10 (7.25–31)68*# (20.5–75)
Immobility (s)90 (50–133.5)85 (65.25–115)130# (92–162)125# (104–145.5)