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Depression Research and Treatment
Volume 2012 (2012), Article ID 350461, 7 pages
http://dx.doi.org/10.1155/2012/350461
Research Article

Joint Effect of Childhood Abuse and Family History of Major Depressive Disorder on Rates of PTSD in People with Personality Disorders

1Department of Psychiatry, Mount Sinai School of Medicine (MSSM), One Gustave L. Levy Place, NY 10029, USA
2Department of Psychiatry, James J. Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA

Received 20 October 2011; Revised 10 January 2012; Accepted 1 February 2012

Academic Editor: Eric Vermetten

Copyright © 2012 Janine D. Flory et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Breslau, R. C. Kessler, H. D. Chilcoat, L. R. Schultz, G. C. Davis, and P. Andreski, “Trauma and posttraumatic stress disorder in the community: the 1996 Detroit area survey of trauma,” Archives of General Psychiatry, vol. 55, no. 7, pp. 626–632, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Creamer, P. Burgess, and A. C. Mcfarlane, “Post-traumatic stress disorder: findings from the Australian National Survey of Mental Health and Well-being,” Psychological Medicine, vol. 31, no. 7, pp. 1237–1247, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. R. C. Kessler, A. Sonnega, E. Bromet, M. Hughes, and C. B. Nelson, “Posttraumatic stress disorder in the national comorbidity survey,” Archives of General Psychiatry, vol. 52, no. 12, pp. 1048–1060, 1995. View at Google Scholar · View at Scopus
  4. J. D. Bremner, S. M. Southwick, D. R. Johnson, R. Yehuda, and D. S. Charney, “Childhood physical abuse and combat-related posttraumatic stress disorder in Vietnam veterans,” American Journal of Psychiatry, vol. 150, no. 2, pp. 235–239, 1993. View at Google Scholar · View at Scopus
  5. J. R. Cougle, K. R. Timpano, N. Sachs-Ericsson, M. E. Keough, and C. J. Riccardi, “Examining the unique relationships between anxiety disorders and childhood physical and sexual abuse in the National Comorbidity Survey-Replication,” Psychiatry Research, vol. 177, no. 1-2, pp. 150–155, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. L. C. Pratchett and R. Yehuda, “Foundations of posttraumatic stress disorder: does early life trauma lead to adult posttraumatic stress disorder?” Development and Psychopathology, vol. 23, no. 2, pp. 477–491, 2011. View at Publisher · View at Google Scholar
  7. R. Yehuda, J. D. Flory, L. C. Pratchett, J. Buxbaum, M. Ising, and F. Holsboer, “Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD,” Psychopharmacology, vol. 212, no. 3, pp. 405–417, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. T. O. Afifi, G. J. G. Asmundson, S. Taylor, and K. L. Jang, “The role of genes and environment on trauma exposure and posttraumatic stress disorder symptoms: a review of twin studies,” Clinical Psychology Review, vol. 30, no. 1, pp. 101–112, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. M. B. Stein, K. L. Jang, S. Taylor, P. A. Vernon, and W. J. Livesley, “Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study,” American Journal of Psychiatry, vol. 159, no. 10, pp. 1675–1681, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. W. R. True, J. Rice, S. A. Eisen et al., “A twin study of genetic and environmental contributions to liability for posttraumatic stress symptoms,” Archives of General Psychiatry, vol. 50, no. 4, pp. 257–264, 1993. View at Google Scholar · View at Scopus
  11. B. J. Milne, A. Caspi, R. Crump et al., “The validity of the family history screen for assessing family history of mental disorders,” American Journal of Medical Genetics B, vol. 150, no. 1, pp. 41–49, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. R. Yehuda, K. C. Koenen, S. Galea, and J. D. Flory, “The role of genes in defining a molecular biology of PTSD,” Disease Markers, vol. 30, no. 2-3, pp. 67–76, 2011. View at Publisher · View at Google Scholar
  13. J. Davidson, M. Swartz, and M. Storck, “A diagnostic and family study of posttraumatic stress disorder,” American Journal of Psychiatry, vol. 142, no. 1, pp. 90–93, 1985. View at Google Scholar · View at Scopus
  14. J. R. T. Davidson, L. A. Tupler, W. H. Wilson, and K. M. Connor, “A family study of chronic post-traumatic stress disorder following rape trauma,” Journal of Psychiatric Research, vol. 32, no. 5, pp. 301–309, 1998. View at Publisher · View at Google Scholar · View at Scopus
  15. E. B. Binder, R. G. Bradley, W. Liu et al., “Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults,” Journal of the American Medical Association, vol. 299, no. 11, pp. 1291–1305, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. P. Xie, H. R. Kranzler, J. Poling et al., “Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder,” Neuropsychopharmacology, vol. 35, no. 8, pp. 1684–1692, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. J. D. Flory, R. Yehuda, R. Grossman, A. S. New, V. Mitropoulou, and L. J. Siever, “Childhood trauma and basal cortisol in people with personality disorders,” Comprehensive Psychiatry, vol. 50, no. 1, pp. 34–37, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Pagura, M. B. Stein, J. M. Bolton, B. J. Cox, B. Grant, and J. Sareen, “Comorbidity of borderline personality disorder and posttraumatic stress disorder in the U.S. population,” Journal of Psychiatric Research, vol. 44, no. 16, pp. 1190–1198, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. J. G. Johnson, P. Cohen, J. Brown, E. M. Smailes, and D. P. Bernstein, “Childhood maltreatment increases risk for personality disorders during early adulthood,” Archives of General Psychiatry, vol. 56, no. 7, pp. 600–608, 1999. View at Publisher · View at Google Scholar · View at Scopus
  20. M. B. First, R. L. Spitzer, M. Gibbon, and J. B.W. Williams, Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), American Psychiatric Press, Washington, DC, USA, 1997.
  21. B. Green, “Psychometric review of Trauma History Questionnaire (self-report),” in Measurement of Stress, Trauma, and Adaptation, B. H. Stamm and E. M Varra, Eds., pp. 366–368, Sidran Press, Lutherville, Md, USA, 1996. View at Google Scholar
  22. B. L. Green, J. H. Rowland, J. L. Krupnick et al., “Prevalence of posttraumatic stress disorder in women with breast cancer,” Psychosomatics, vol. 39, no. 2, pp. 102–111, 1998. View at Google Scholar · View at Scopus
  23. K. T. Mueser, L. B. Goodman, S. L. Trumbetta et al., “Trauma and posttraumatic stress disorder in severe mental illness,” Journal of Consulting and Clinical Psychology, vol. 66, no. 3, pp. 493–499, 1998. View at Publisher · View at Google Scholar
  24. B. Pfohl, N. Blum, and M. Zimmerman, Structured Interview for DSM-IV Personality (SIDP-IV), American Psychiatric Press, Washington, DC, USA, 1997.
  25. NIMH Genetics Initiative, Family Interview for Genetic Studies (FIGS), National Institute of Mental Health, Rockville, Md, USA, 1992.
  26. D. P. Bernstein and L. Fink, Childhood Trauma Questionnaire: A Retrospective Report, Harcourt Brace & Company, San Antonio, Tex, USA, 1998.
  27. D. P. Bernstein, L. Fink, L. Handelsman et al., “Initial reliability and validity of a new retrospective measure of child abuse and neglect,” American Journal of Psychiatry, vol. 151, no. 8, pp. 1132–1136, 1994. View at Google Scholar · View at Scopus
  28. C. S. Widom, K. DuMont, and S. J. Czaja, “A prospective investigation of major depressive disorder and comorbidity in abused and neglected children grown up,” Archives of General Psychiatry, vol. 64, no. 1, pp. 49–56, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. D. N. Klein, P. M. Lewinsohn, P. Rohde, J. R. Seeley, and C. E. Durbin, “Clinical features of major depressive disorder in adolescents and their relatives: impact on familial aggregation, implications for phenotype definition, and specificity of transmission,” Journal of Abnormal Psychology, vol. 111, no. 1, pp. 98–106, 2002. View at Publisher · View at Google Scholar · View at Scopus
  30. B. J. Milne, A. Caspi, H. Harrington, R. Poulton, M. Rutter, and T. E. Moffitt, “Predictive value of family history on severity of illness: the case for depression, anxiety, alcohol dependence, and drug dependence,” Archives of General Psychiatry, vol. 66, no. 7, pp. 738–747, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. M. M. Weissman, P. Wickramaratne, Y. Nomura, V. Warner, D. Pilowsky, and H. Verdeli, “Offspring of depressed parents: 20 Years later,” American Journal of Psychiatry, vol. 163, no. 6, pp. 1001–1008, 2006. View at Publisher · View at Google Scholar · View at Scopus
  32. L. A. Clark, G. Kochanska, and R. Ready, “Mothers' personality and its interaction with child temperament as predictors of parenting behavior,” Journal of Personality and Social Psychology, vol. 79, no. 2, pp. 274–285, 2000. View at Google Scholar · View at Scopus
  33. A. Charuvastra and M. Cloitre, “Social bonds and posttraumatic stress disorder,” Annual Review of Psychology, vol. 59, pp. 301–328, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. A. F. Lieberman, P. Van Horn, and E. J. Ozer, “Preschooler witnesses of marital violence: predictors and mediators of child behavior problems,” Development and Psychopathology, vol. 17, no. 2, pp. 385–396, 2005. View at Google Scholar
  35. V. J. Edwards, G. W. Holden, V. J. Felitti, and R. F. Anda, “Relationship between multiple forms of childhood maltreatment and adult mental health in community respondents: results from the adverse childhood experiences study,” American Journal of Psychiatry, vol. 160, no. 8, pp. 1453–1460, 2003. View at Publisher · View at Google Scholar · View at Scopus
  36. J. G. Green, K. A. McLaughlin, P. A. Berglund et al., “Childhood adversities and adult psychiatric disorders in the national comorbidity survey replication I: associations with first onset of DSM-IV disorders,” Archives of General Psychiatry, vol. 67, no. 2, pp. 113–123, 2010. View at Publisher · View at Google Scholar · View at Scopus
  37. J. Hardt and M. Rutter, “Validity of adult retrospective reports of adverse childhood experiences: review of the evidence,” Journal of Child Psychology and Psychiatry and Allied Disciplines, vol. 45, no. 2, pp. 260–273, 2004. View at Publisher · View at Google Scholar · View at Scopus