Clinical Study

Lovastatin as an Adjuvant to Lithium for Treating Manic Phase of Bipolar Disorder: A 4-Week, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Table 3

The rate of adverse effects in both groups.

Lovastatin group
(%)
Placebo group
(%)
value

Constipation 01 (4.0%)
Dizziness 6 (26.1)3 (33.3)0.1
Hypotension 1 (4.3)1 (4.0%)
Dry mouth 1 (4.3)0
Blurred vision00
Sweating 01 (4.0%)
Urinary disturbance 00
Tremor10 (43.5)18 (72)0.04
Anorexia00
Nervousness 3 (13)9 (39.0)
Agitation 6 (30)14 (56.0)0.045
Headache 00
Insomnia00
Diarrhea 00
Nausea 10 (43.5)14 (56.0)
Drowsiness 6 (26.1) 3 (12.0)
Rash 02 (8.0)
Cramps 00
Myalgia 00