A Preliminary Study on the Relationship between Platelet Serotonin Transporter Functionality, Depression, and Fatigue in Patients with Untreated Chronic Hepatitis C

Table 4

Chi-Square Test of association between the predictor variables and the likelihood of depression.

Predictor variables	Total	Depression	𝜒^2/𝑃	Relative risk (95% CI)
Overweight
BMI>25 kg/m^2	29	8 (27.6%)	2.896, 𝑃=0.089	2.483 (0.830–7.429)
BMI≤25 kg/m^2	36	4 (11.1%)
Thrombocytopenia
Yes	17	7 (41.2%)	7.891, P = 0.005	3.953 (1.446–10.805)
No	48	5 (10.4%)
BFI interference score
≥3 (moderate to severe)	18	9 (50.0%)	14.863, P < 0.001	7.167 (2.191–23.443)
<3 (absent to mild)	43	3 (7.0%)
BFI intensity score
7–10 (moderate to severe)	35	9 (25.7%)	3.056, 𝑃=0.080	3.214 (0.759–13.616)
0–6 (no to mild)	25	2 (8.0%)
5HT uptake groups
>75th percentile	26	9 (34.6%)	7.512, P = 0.006	4.50 (1.344–15.072)
≤75th percentile	39	3 (7.7%)
5HT content groups
>75th percentile	28	7 (25.0%)	1.397, 𝑃=0.237	1.850 (0.656–5.220)
≤75th percentile	37	5 (13.5%)