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Diagnostic and Therapeutic Endoscopy
Volume 4 (1997), Issue 2, Pages 75-81
http://dx.doi.org/10.1155/DTE.4.75

Photodynamic Therapy With YAG-OPO Laser for Early Stage Lung Cancer

1Department of Surgery, Tokyo Medical College, Nishishinjuku, Shinjuku-ku, Tokyo 160, Japan
2Department of Internal Medicine, National Kinki Central Hospital, The Center for Adult Disease, Osaka, Japan
3Department of Field Research, The Center for Adult Disease, Osaka, Japan
44th Department of Internal Medicine, The Center for Adult Disease, Osaka, Japan
5Department of Pulmonary Medicine, Osaka City General Hospital, Osaka, Japan
62nd Department of Internal Medicine, Osaka Prefectural Habikino Hospital, Osaka, Japan

Received 13 March 1997; Accepted 30 May 1997

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Photodynamic therapy (PDT) utilizing Photofrin is proving to be effective for the treatment of early stage lung cancers. The effect of PDT utilizing YAG-OPO laser as new light source was evaluated in 26 patients (29 lesions) with early stage lung cancers. YAG-OPO laser is solid state tunable laser which is easy to change wavelength between 620 and 670 nm exciting various kinds of photosensitizers. Moreover, YAG-OPO laser is more reliable, smaller and has less consumables than argon-dye laser or excimer-dye laser. As the result of PDT with YAG-OPO laser, complete remission (CR) was obtained in 82.6% of the 29 lesions, partial remission (PR) in 13.8% and no change (NC) was obtained in 3.4%. We conclude that PDT utilizing YAG-OPO laser is efficacious in the treatment of early stage lung cancers and can achieve complete remission.