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Diagnostic and Therapeutic Endoscopy
Volume 3 (1997), Issue 3, Pages 171-175

Effect of Diazepam Sedation on Arterial Oxygen Saturation and Patient Tolerance During Esophagogastroduodenoscopy

1Department of Medicine, Government S.M.H.S. Hospital, Medical College, Srinagar, Kashmir 190 010, India
2Nalbandpora Safakadal, Srinagar, Kashmir 190 002, India

Received 27 May 1996; Accepted 2 September 1996

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The impact of intravenous (I/V) diazepam sedation on arterial oxygen saturation (SaO2) and patient tolerance was studied in 100 patients in the age group of (27–60) years, who were subjected to esophagogastroduodenoscopy (EGD) for different indications. Equal number of patients in the same age group, who did not receive the sedation acted as controls. It was observed that SaO2 showed a transient fall during the first few minutes of the endoscopic procedure even without sedation and diazepam administration did not significantly (p > 0.05) aggravate this oxygen desaturation. It was also observed that diazepam sedation increased the procedure tolerance of the patients when compared with controls (p < 0.01). In conclusion, it was inferred that I/V diazepam may act as a safe and favourable sedative for EGD.