Diagnostic and Therapeutic Endoscopy

Diagnostic and Therapeutic Endoscopy / 1999 / Article
Special Issue

Autofluorescence Endoscopy

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Open Access

Volume 5 |Article ID 648743 | https://doi.org/10.1155/DTE.5.91

T. Horvath, M. Horvathova, F. Salajka, B. Habanec, L. Foretova, J. Kana, H. Koukalova, P. Pafko, F. Wurst, E. Novotna, J. Pecina, V. Vagunda, R. Vrbacky, R. Talac, H. Coupková, Z. Pacovsky, "Detection of Bronchial Neoplasia in Uranium Miners by Autofluorescence Endoscopy (SAFE-1000)", Diagnostic and Therapeutic Endoscopy, vol. 5, Article ID 648743, 8 pages, 1999. https://doi.org/10.1155/DTE.5.91

Detection of Bronchial Neoplasia in Uranium Miners by Autofluorescence Endoscopy (SAFE-1000)


The increase in the detection rate for premalignant changes of bronchial epithelium was studied in 56 symptom-free volunteers from the risk group of Czech uranium miners (mean age 50.69 years, mean WLM 21.06 (1 Working Level Month is equal to the absorption of latent energy of 2.08 × 10–5 J/m3 in one month, i.e. 170 working hours)) by the additional employment of the System of Autofluorescence Endoscopy (SAFE-1000 Pentax) to conventional white-light bronchoscopy, comparing results with those of bronchial biopsy histopathology examination. Histopathology using hematoxylin and eosin staining confirmed intraepithelial neoplasias in 15 areas in 10 persons. White-light bronchoscopy sensitivity was 21.05%, and specificity 93.7% which an autofluorescence bronchoscopy sensitivity was 78.95% and specificity 81.89%.

Copyright © 1999 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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