Clinical Study
Small-Bowel Capsule Endoscopy in Patients with Suspected Crohn's Disease—Diagnostic Value and Complications
Table 4
Value of different criteria in the diagnosis of CD.
| | Sens. (95%CI) | Spec. (95%CI) | PPV (95%CI) | NPV (95%CI) | LLR+ (95%CI) | LLR− (95%CI) |
| Lesions on SBCE | 93 (75–98) | 80 (64–90) | 77 (59–88) | 94 (79–99) | 4.7 (2.5–8.9) | 0.08 (0.02–0.3) | ICCE criteria | 65 (45–81) | 58 (42–73) | 52 (35–69) | 70 (52–84) | 1.5 (1–2.4) | 0.58 (0.34–1) | plus lesions on SBCE | 100 (70–100) | 86 (64–96) | 85 (61–86) | 100 (79–100) | 7.3 (2.5–20) | 0 | Symptoms plus extraint.symptoms/signs | 24 (11–43) | 70 (54–83) | 36 (17–61) | 56 (42–70) | 0.8 (0.3–1.8) | 1.0 (0.8–1.34) | plus lesions on SBCE | 77 (40–96) | 100 (80–100) | 100 (50–100) | 91 (70–98) | (a) | 0.22 (0.06–0.7) | Symptoms plus abnormal imaging | 29 (13–51) | 91 (75–97) | 70 (35–91) | 65 (50–77) | 3.4 (0.9–11) | 0.77 (0.59–1) | plus lesions on SBCE | 100 (46–100) | 96 (80–99) | 83 (36–99) | 100 (84–100) | 29 (4,2–198) | 0 | Symptoms plus Inflammatory markers | 55 (35–73) | 78 (61–88) | 64 (42–81) | 71 (55–83) | 2.5 (1.2–4.8) | 0.57 (0.37–0.8) | plus lesions on SBCE | 88 (863–98) | 96 (78–99) | 94 (69–99) | 92 (74–98) | 23.1 (3.3–159) | 0.1 (0.03–0.4) |
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Sens.: sensitivity; Spec.: specificity; PPV: positive predictive value; NPV: negative predictive value; LLR+: likelihood ratio positive; LLR−: likelihood ratio negative; CI: Confidence Interval; extraint.: extraintestinal; (a)infinity.
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