Proton Pump Inhibitor Therapy before and after Endoscopic Submucosal Dissection: A Review

Table 1

Delayed bleeding rate of endoscopic submucosal dissection for gastric cancer and gastric adenoma in Japanese patients.

Author	Year	Lesions	Delayed bleeding (%)	Resection rate (%)
Imagawa et al. [13]	2006	196	0	93
Kakushima et al. [14]	2006	383	3.4	91
Oka et al. [5]	2006	195	6.2	83
Onozato et al. [15]	2006	171	7.6	94
Hirasaki et al. [16]	2007	112	7.1	96
Ono et al. [17]	2008	161	8.7	99
Isomoto et al. [18]	2009	510	1.8	95
Hoteya et al. [19]	2009	572	4.9	95
Tsuji et al. [20]	2010	398	5.8	NA
Higashiyama et al. [21]	2011	924	3.0	NA
Kawano et al. [22]	2011	91	2.2	97.8
Imaeda et al. [23]	2011	123	4.1	97.7
Akasaka et al. [24]	2011	1188	3.1	95
Goto et al. [25]	2012	1814	5.5	NA
Total		6838	2.6 (95% CI: 2.3–3.1)

NA: not analyzed; CI: confidence interval.