Review Article

Endoscopic Papillary Large Balloon Dilation Reduces the Need for Mechanical Lithotripsy in Patients with Large Bile Duct Stones: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.

Study (year) CountryType of studyNumber of patients
ES/ES + EPLBD
Age (mean)
ES/ES + EPLBD
Gender, M (%)
ES/ES + EPLBD
Mean CBD diameter (mm ± SD)
ES/ES + EPLBD
Large balloon dilation size (mm)Mean size of the stone (mm ± SD) ES/ES + EPLBDSize of ES
ES/ES + EPLBD
Periampullary diverticulum (%)
ES/ES + EPLBD

Heo (2007) KoreaRCT100/10063/6450/48N/A12–2015 ± 0.7/16 ± 0.7Full/Limited45/49
Itoi (2009) JapanRetrospective48/5373/7558/3818 ± 4.3/17 ± 3.715–2015 ± 3.2/15 ± 3.5Full/Full58/47
Kim HG (2009) KoreaRCT28/2770/7039/3721 ± 5.7/21 ± 6.315–1821 ± 5.2/21 ± 4.1Full/Limited36/33
Hong GY (2009) KoreaRetrospective65/70N/AN/AN/A15 or 20N/AN/A49/57
Kim TH (2011) KoreaRetrospective77/7269/6949/5419 ± 4.4/18 ± 3.3N/AN/AFull/LimitedN/A
Teoh (2013) ChinaRCT78/7373/7251/44N/A15N/AFull/LimitedNA
Rosa (2013) PortugalRetrospective43/6873/7135/3416.4 ± 7.2/17.1 ± 3.412–1816.0 ± 6.7/16.8 ± 4.4N/AN/A

RCT: randomized controlled trial; ES: endoscopic sphincterotomy; EPLBD: endoscopic papillary large balloon dilation; N/A: not available; CBD: common bile duct; SD: standard deviation.