Long-Term Endoscopic Follow-Up of Patients with Chronic Radiation Proctopathy after Brachytherapy for Prostate Cancer

Table 3

Clinical parameters associated with rectal bleeding.

Parameter	Grade ≥ 1 rectal bleeding (%)	p value
Age, years
≥70	14/43 (32.5)	0.11
<70	11/61 (18.0)
Stage
T1	19/81 (23.4)	0.79
T2	6/23 (26.1)
Use of antithrombotic drugs
Yes	7/21 (33.3)	0.27
No	18/83 (21.6)
Presence of DM
Yes	2/12 (16.6)	0.73
No	23/92 (25.0)
Prostate volume, cc
≥25	11/49 (22.4)	0.82
<25	14/55 (25.4)
EBRT boost
Yes	22/53 (41.5)	<0.0001
No	3/51 (5.9)
Number of seeds
≥70	10/52 (19.2)	0.35
<70	15/52 (28.8)
Use of ADT
Yes	8/39 (21.0)	0.64
No	17/65 (10.8)

DM, diabetes mellitus; EBRT, external-beam radiotherapy; ADT, androgen deprivation therapy.