Evidence-Based Complementary and Alternative Medicine

Evidence-Based Complementary and Alternative Medicine / 2008 / Article

Review | Open Access

Volume 5 |Article ID 149354 | https://doi.org/10.1093/ecam/nem089

Jennie C. I. Tsao, Subhadra Evans, Marcia Meldrum, Tamara Altman, Lonnie K. Zeltzer, "A Review of CAM for Procedural Pain in Infancy: Part II. Other Interventions", Evidence-Based Complementary and Alternative Medicine, vol. 5, Article ID 149354, 9 pages, 2008. https://doi.org/10.1093/ecam/nem089

A Review of CAM for Procedural Pain in Infancy: Part II. Other Interventions

Received09 Feb 2007
Accepted24 Apr 2007


This article is the second in a two-part series reviewing the empirical evidence for complementary and alternative medicine (CAM) approaches for the management of pain related to medical procedures in infants up to 6 weeks of age. Part I of this series investigated the effects of sucrose with or without non-nutritive sucking (NNS). The present article examines other CAM interventions for procedural pain including music-based interventions, olfactory stimulation, kangaroo care and swaddling. Computerized databases were searched for relevant studies including prior reviews and primary trials. Preliminary support was revealed for the analgesic effects of the CAM modalities reviewed. However, the overall quality of the evidence for these approaches remains relatively weak. Additional well-designed trials incorporating rigorous methodology are required. Such investigations will assist in the development of evidence-based guidelines on the use of CAM interventions either alone or in concert with conventional approaches to provide safe, reliable analgesia for infant procedural pain.

Copyright © 2008 Jennie C. I. Tsao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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