Original Article | Open Access
Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots
Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explore the antifertility and estrogenic activity of ethanolic extract of the roots of Hibiscus rosa-sinensis Linn. A strong anti-implantation (inhibition 100%) and uterotropic activity was observed at the dose level of 400 mg/kg body weight. Histological studies were carried out to confirm this effect.
Copyright © 2008 Neeru Vasudeva and S. K. Sharma. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.