Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on Its Dopaminergic Effects

Table 2

Effect of T. catigua extract on Haloperidol (1 mg kg⁻¹, i.p.)-induced catalepsy

Treatments	Catalepsy time (s)
PBS + PBS	1.8  ±  0.8
PBS + Haloperidol	58.4  ±  13.75***
PBS +  T. catigua (200 mg kg^−1)	2.0  ±  0.6
PBS +  T. catigua (400 mg kg^−1)	2.2  ±  0.6
T. catigua (200 mg kg^−1) + Haloperidol	31.4  ±  2.4^*,b
T. catigua (400 mg kg^−1) + Haloperidol	13.3  ±  3.7^c,$

Each group represents the mean  ±  SEM of 10 animals.
*** 𝑃<.001, *𝑃<.05 compared with PBS; ^b𝑃<.001 compared with Haloperidol; ^$𝑃<.001 compared with T. catigua (200 mg kg⁻¹) + Haloperidol.