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Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 132374, 14 pages
http://dx.doi.org/10.1093/ecam/nep088
Original Article

S-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness

1Department of Internal Medicine, Taipei Medical University Hospital, Taiwan
2Graduate Institute of Pharmacology, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
3Department of Medical Technology, College of Medicine, Taipei Medical University, Taiwan
4National Research Institute of Chinese Medicine, Taipei, Taiwan

Received 30 March 2009; Accepted 15 June 2009

Copyright © 2011 Chung-Hung Shih et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Sajida Abdureyim, Nurmuhammat Amat, Anwar Umar, Halmurat Upur, Benedicte Berke, and Nicholas Moore, “Anti-Inflammatory, Immunomodulatory, and Heme Oxygenase-1 Inhibitory Activities of Ravan Napas, a Formulation of Uighur Traditional Medicine, in a Rat Model of Allergic Asthma,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, pp. 1–13, 2011. View at Publisher · View at Google Scholar
  • Wen-Chung Huang, and Chian-Jiun Liou, “Dietary Acacetin Reduces Airway Hyperresponsiveness and Eosinophil Infiltration by Modulating Eotaxin-1 and Th2 Cytokines in a Mouse Model of Asthma,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, pp. 1–11, 2012. View at Publisher · View at Google Scholar
  • Jerzy Tys, Aleksandra Szopa, Mariola Chmielewska, Anna Serefko, Justyna Lalak, and Ewa Poleszak, “A botanical and pharmacological description of petasites species,” Current Issues in Pharmacy and Medical Sciences, vol. 28, no. 3, pp. 151–154, 2015. View at Publisher · View at Google Scholar
  • Min-Soo Noh, Young-Geun Lee, Young-Whan Choi, Kyoung-Pil Lee, Dong-Soon Im, Saeromi Kang, Soo-Jin Park, Jung-Min Kim, Hae Young Chung, and Nam Kyung Je, “Therapeutic effects of S-petasin on disease models of asthma and peritonitis,” Biomolecules and Therapeutics, vol. 23, no. 1, pp. 45–52, 2015. View at Publisher · View at Google Scholar
  • Jan Beute, Vincent Manganiello, and Alex KleinJan, “Phosphodiesterase 3 and 4 Inhibition: Facing a Bright Future in Asthma Control,” Asthma Diagnosis and Management - Approach Based on Phenotype and Endotype, 2018. View at Publisher · View at Google Scholar