S-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness

Figure 6

Effects of S-petasin (10–30 𝜇mol/kg, s.c.) on the total IgG_2a (a) level in the serum, and total IgE (b, d) and OVA-specific IgE (c, e) levels in the serum (b, c) and BALF (d, e) of sensitized mice which received aerosolized MCh (6.25–50 mg/mL) 2 days after secondary allergen challenge. ^∗𝑃<.05 and ^∗∗𝑃<.01, compared to the vehicle (control). Each value represents the mean ± SEM. The number of mice in each group was 10.

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