Abnormal Savda Munziq, an Herbal Preparation of Traditional Uighur Medicine, May Prevent 1,2-dimethylhydrazine-Induced Rat Colon Carcinogenesis

Table 3

Effect of ASMq ethanol extract on aberrant crypt multiplicity in DMH-treated rats (mean ± SD).

Groups/treatment	Number of rats	ACF ≤ 3	ACF ≥ 4	AC/ACF
Normal control (NS)	8	0	0	—
Negative control (DMH + NS)	8	39.3±14.3	11.0±3.9	2.6±0.2
Pretreatment (DMH + ASMq 400)	8	32.9±14.2	9.0±7.3^∗	2.4±0.4^∗
Pretreatment (DMH + ASMq 800)	8	32.3±11.2	6.5±3.3^∗	2.3±0.2^∗
Pretreatment (DMH + ASMq 1600)	8	19.6±12.5^∗	3.4±2.9^∗	2.3±0.5^∗
Treatment (DMH + ASMq 400)	8	27.8±9.0^∗	8.1±3.3^∗	2.5±0.2
Treatment (DMH + ASMq 800)	8	24.6±13.3^∗	6.4±4.1^∗	2.6±0.4
Treatment (DMH + ASMq 1600)	8	19.9±7.3^∗	2.5±2.9^∗	2.0±0.4^∗

^∗𝑃<.05 as compared with negative control group.