Increased Survivorship and Altered Cytokine Profile from Treatment of Influenza A H1N1-Infected Mice with Ekybion: A Drug Complex of Natural Extracts and Inorganic Compounds
Figure 2
Toxicity of Ekybion in Balb/c mice. (a) Twenty uninfected 8-week old female Balb/c mice were treated with 1X Ekybion every 8 hours for 10 days. Toxicity was determined by changes in daily weight compared to twenty untreated control animals. (b) Two animals from each group were euthanized on day 4 of treatment and lung tissue collected for histological examination for tissue damage or inflammation. Histological examination revealed no inflammation in treated or untreated control animals. (c) Two mice per group were treated every 8 hours for three days with Ekybion at the indicated concentrations and weighed daily to determine toxicity. ( by Two-Way ANOVA with Bonferroni posttests).
