Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 282151, 7 pages
Original Article

North American (Panax quinquefolius) and Asian Ginseng (Panax ginseng) Preparations for Prevention of the Common Cold in Healthy Adults: A Systematic Review

1School of Public Health, University of Alberta, 650 University Terrace, Edmonton, Alberta, Canada T6G 2T4
2Durec Information Services Inc., St Albert, Alberta, Canada

Received 3 October 2008; Accepted 3 June 2009

Copyright © 2011 Jennifer Krebs Seida et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Heikkinen and A. Järvinen, “The common cold,” The Lancet, vol. 361, no. 9351, pp. 51–59, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. P. M. Barnes, E. Powell-Griner, K. McFann, and R. L. Nahin, “Complementary and alternative medicine use among adults: United States, 2002,” Advance data, no. 343, pp. 1–19, 2004. View at Google Scholar · View at Scopus
  3. CV Technologies, “COLD-fX [Internet],” July 2008,
  4. A. R. Jadad, R. A. Moore, D. Carroll et al., “Assessing the quality of reports of randomized clinical trials: is blinding necessary?” Controlled Clinical Trials, vol. 17, no. 1, pp. 1–12, 1996. View at Publisher · View at Google Scholar · View at Scopus
  5. K. F. Schulz, L. Chalmers, R. J. Hayes, and D. G. Altman, “Empirical evidence of bias: dimensions of methodological quality associated with estimates of treatment effects in controlled trials,” Journal of the American Medical Association, vol. 273, no. 5, pp. 408–412, 1995. View at Publisher · View at Google Scholar · View at Scopus
  6. Review Manager 4.2 (RevMan) [Computer program], Copenhagen:The Nordic Cochrane Centre, The Cochrane Collaboration.
  7. J. J. Deeks, J. P. T. Higgins, and D. G. Altman, “Analysing and presenting results,” in Cochrane Handbook for Systematic Reviews of Interventions 4.2.6, J. P. T. Higgins and S. Green, Eds., John Wiley & Sons, Chichester, UK, Section 8, The Cochrane Library, no. 4, 2006.
  8. J. E. McElhaney, S. Gravenstein, S. K. Cole, E. Davidson, D. O'Neill, S. Petitjean et al., “A placebo-controlled trial of a proprietary extract of North American ginseng (CVT-E002) to prevent acute respiratory illness in institutionalized older adults,” Journal of the American Geriatrics Society, vol. 52, pp. 13–19, 2004. View at Google Scholar
  9. F. Scaglione, G. Cattaneo, M. Alessandria, and R. Cogo, “Efficacy and safety of the standardised Ginseng extract G115 for potentiating vaccination against the influenza syndrome and protection against the common cold [corrected],” Under Experimental and Clinical Research, vol. 22, pp. 65–72, 1996. View at Google Scholar
  10. G. N. Predy, V. Goel, R Lovlin, A. Donner, L. Stitt, and TK Basu, “Efficacy of an extract of North American ginseng containing poly-furanosyl-pyranosyl-saccharides for preventing upper respiratory tract infections: a randomized controlled trial,” Canadian Medical Association Journal, vol. 173, pp. 1043–1048, 2005. View at Google Scholar
  11. J. E. McElhaney, V. Goel, B. Toane, J. Hooten, and J. J. Shan, “Efficacy of COLD-fX in the prevention of respiratory symptoms in community-dwelling adults: a randomized, double-blinded, placebo controlled trial,” Journal of Alternative and Complementary Medicine, vol. 12, pp. 153–157, 2006. View at Google Scholar