Total Flavonoids Extracted from Xiaobuxin-Tang on the Hyperactivity of Hypothalamic-Pituitary-Adrenal Axis in Chronically Stressed Rats

<table>Main molecular targets of XBXT-2 that underlie its antidepressant-like effect. Arrows indicate down-regulation or up-regulation. CRF, corticotropin-releasing factor; ACTH, adrenocorticotropic hormone; GC, glucocorticoids; GR, glucocorticoid receptors.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Total Flavonoids Extracted from Xiaobuxin-Tang on the Hyperactivity of Hypothalamic-Pituitary-Adrenal Axis in Chronically Stressed Rats 