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Evidence-Based Complementary and Alternative Medicine
Volume 2011 (2011), Article ID 512697, 5 pages
Original Article

Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System

1Oriental Medicine Research Center, The Kitasato Institute, Japan
2Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan

Received 13 September 2007; Accepted 30 May 2008

Copyright © 2011 N. Ito et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. Andrade, J. J. Caraveo-Anduaga, P. Berglund, R. V. Bijl, R. De Graaf, and W. Vollebergh, “The epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) Surveys,” International Journal of Methods in Psychiatric Research, vol. 12, pp. 3–21, 2003. View at Google Scholar
  2. T. Komori, R. Fujiwara, M. Tanida, and J. Nomura, “Potential antidepressant effects of lemon odor in rats,” European Neuropsychopharmacology, vol. 5, no. 4, pp. 477–480, 1995. View at Publisher · View at Google Scholar
  3. N. Ito, T. Nagai, T. Yabe, S. Nunome, T. Hanawa, and H. Yamada, “Antidepressant-like activity of a Kampo (Japanese herbal) medicine, Koso-san (Xiang-Su-San), and its mode of action via the hypothalamic-pituitary-adrenal axis,” Phytomedicine, vol. 13, no. 9-10, pp. 658–667, 2006. View at Publisher · View at Google Scholar · View at PubMed
  4. L. Luo, J. Nong Wang, L. D. Kong, Q. G. Jiang, and R. X. Tan, “Antidepressant effects of Banxia Houpu decoction, a traditional Chinese medicinal empirical formula,” Journal of Ethnopharmacology, vol. 73, no. 1-2, pp. 277–281, 2000. View at Publisher · View at Google Scholar
  5. H. Takeda, M. Tsuji, M. Inazu, T. Egashira, and T. Matsumiya, “Rosmarinic acid and caffeic acid produce antidepressive-like effect in the forced swimming test in mice,” European Journal of Pharmacology, vol. 449, no. 3, pp. 261–267, 2002. View at Publisher · View at Google Scholar
  6. M. J. Detke, J. Johnson, and I. Lucki, “Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression,” Experimental and Clinical Psychopharmacology, vol. 5, no. 2, pp. 107–112, 1997. View at Publisher · View at Google Scholar
  7. R. D. Porsolt, A. Bertin, and M. Jalfre, “Behavioral despair in mice: a primary screening test for antidepressants,” Archives Internationales de Pharmacodynamie et de Therapie, vol. 229, no. 2, pp. 327–336, 1977. View at Google Scholar
  8. L. C. Solberg, T. H. Horton, and F. W. Turek, “Circadian rhythms and depression: effects of exercise in an animal model,” American Journal of Physiology, vol. 276, no. 1, pp. R152–R161, 1999. View at Google Scholar
  9. P. Willner, A. Towell, D. Sampson, S. Sophokleous, and R. Muscat, “Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant,” Psychopharmacology, vol. 93, no. 3, pp. 358–364, 1987. View at Google Scholar
  10. J. R. Alberts and B. G. Galef Jr., “Acute anosmia in the rat: a behavioral test of a peripherally-induced olfactory deficit,” Physiology and Behavior, vol. 6, no. 5, pp. 619–621, 1971. View at Google Scholar
  11. N. Mikuriya, Y. Kim, and K. Fujimura, “The effect of the aroma of patchouli essential oil on defecation and constipation,” Aroma Research, vol. 5, pp. 70–75, 2004. View at Google Scholar
  12. A. Sugaya, T. Tsuda, and T. Obuchi, “Pharmacological studies on Perillae Herba. I. Neuropharmacological action of water extract and perillaldehyde,” Yakugaku Zasshi, vol. 101, pp. 642–648, 1981 (Japanese). View at Google Scholar
  13. J. R. Alberts and M. I. Friedman, “Olfactory bulb removal but not anosmia increases emotionality and mouse killing,” Nature, vol. 238, no. 5365, pp. 454–455, 1972. View at Publisher · View at Google Scholar
  14. D. A. Edwards, “Non sensory involvement of the olfactory bulbs in the mediation of social behaviors,” Behavioral Biology, vol. 11, no. 3, pp. 287–302, 1974. View at Google Scholar
  15. M. H. Sieck and H. D. Baumbach, “Differential effects of peripheral and central anosmia producing techniques on spontaneous behavior patterns,” Physiology and Behavior, vol. 13, no. 3, pp. 407–425, 1974. View at Publisher · View at Google Scholar