Anticancer Potentials of Root Extract of Polygala senega and Its PLGA Nanoparticles-Encapsulated Form

Table 2

Band density of different mRNA expressions in different series. Band density was expressed as a mean ± SE of the three independent experiments. Significant differences between EEPS and NEEPS are indicated by *(𝑃<.05), **(𝑃<.01) and ***(𝑃<.001).

Signalling molecule	Band density
	Ln1 (Control)	Ln2 (EEPS 100 𝜇g)	Ln3 (EEPS 200 𝜇g)	Ln4 (NEEPS 100 𝜇g)	Ln5 (NEEPS 200 𝜇g)
𝛽-actin	3.52±0.015	3.54±0.035	3.5±0.052	3.48±0.032	3.52±0.028
Survivin	7.6±0.21	6.8±0.125	5.8±0.32	6.15±0.185^∗	4.2±0.15^∗
PCNA	8.25±0.15	7.5±0.12	6.25±0.25	6.58±0.15^∗∗	4.85±0.125^∗∗
Caspase-3	9.21±0.13	11.5±0.18	13.52±0.15	12.42±0.12^∗	15.4±0.35^∗∗
p53	6.8±0.74	7.2±0.32	9.25±0.15	8.85±0.4^∗	11.52±0.16^∗∗∗

^∗𝑃<.05, ^∗∗𝑃<.01, ^∗∗∗𝑃<.001.