Emodin Induces Apoptotic Death in Murine Myelomonocytic Leukemia WEHI-3 Cells In Vitro and Enhances Phagocytosis in Leukemia Mice In Vivo
Figure 9
Emodin affected on phagocytosis by monocytes and macrophages from leukemia BALB/c mice. Mice were injected with WEHI-3 cells ( cells/100 μL) in PBS for 2 weeks and treated without or with emodin for 2 weeks. Leukocytes were collected from PBMC (a) and peritoneal cavity (b) from animals and were analyzed for phagocytosis by flow cytometry as described in Section 2. Each point is the mean ± SD and similar results were observed in at least three independent samples (), and * and *** () were shown significant followed by one-way ANOVA followed by Dunnett’s test.
