Ethanolic Extract of Propolis Augments TRAIL-Induced Apoptotic Death in Prostate Cancer Cells
Figure 5
Cytotoxic activity of TRAIL in combination with EEP, after and before exposure to EEP in prostate cancer cells. (a) LNCaP and (b) DU145 cancer cells were as follws: (1) treated with EEP in combination with TRAIL for 48 h; (2) pretreated with EEP for 24 h, followed by TRAIL for another 24 h; and (3) pretreated with TRAIL for 24 h, followed by EEP for another 24 h. The percentage of cell deaths was measured by MTT cytotoxicity assay. The values represent mean ± SD of three independent experiments performed in quadruplicate (n = 12). All differences are statistically significant in relation to control (P < .05).
