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Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 543216, 12 pages
http://dx.doi.org/10.1155/2011/543216
Review Article

Zingiber zerumbet (L.) Smith: A Review of Its Ethnomedicinal, Chemical, and Pharmacological Uses

1Department of Pharmaceutics, Faculty of Pharmacy, MARA University of Technology, Puncak Alam Campus, Bandar Puncak Alam, 42300 Selangor, Malaysia
2Pharmacogenomics Center, Faculty of Pharmacy, MARA University of Technology, Shah Alam, 40450 Selangor, Malaysia
3Department of Biomedical Sciences, Faculty of Medicine and Health Science, Putra Malaysia University, UPM Serdang, 43400 Selangor, Malaysia

Received 28 August 2010; Revised 12 December 2010; Accepted 18 January 2011

Copyright © 2011 N. J. Yob et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Zingiber zerumbet Sm., locally known to the Malay as “Lempoyang,” is a perennial herb found in many tropical countries, including Malaysia. The rhizomes of Z. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory- and pain-mediated diseases, worm infestation and diarrhea). Research carried out using different in vitro and in vivo assays of biological evaluation support most of these claims. The active pharmacological component of Z. zerumbet rhizomes most widely studied is zerumbone. This paper presents the botany, traditional uses, chemistry, and pharmacology of this medicinal plant.