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Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 543648, 8 pages
Original Article

An Herbal Nasal Drop Enhanced Frontal and Anterior Cingulate Cortex Activity

1Neuropsychology Laboratory, Department of Psychology, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
2Integrative Neuropsychological Rehabilitation Center, The Chinese University of Hong Kong, Hong Kong
3Henan Songshan Research Institute for Chanwuyi, Hong Kong
4Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hong Kong

Received 14 May 2009; Accepted 26 October 2009

Copyright © 2011 Agnes S. Chan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The present study examined the neuro-electrophysiological activity of the brain associated with the application of a herbal remedy developed by a Shaolin monk based upon the Chan healing principle of clearing the orifices (i.e., the nasal cavities). A repeated-measures design was used. Fourteen normal adults were administered herbal remedy and saline solution intranasally on separate sessions. Two intervals of eyes-closed resting EEG data were obtained individually before and after each administration. Results showed that only the herbal remedy but not the saline solution induced elevation in cordance, an index correlated with cerebral perfusion, in the anterior brain region. In addition, the activity of the anterior cingulate cortex (ACC), as examined by the LORETA analysis, was also increased after the application of the herbal remedy but not saline solution. The present study provided some preliminary evidence suggesting that the herbal nasal drop enhanced the activity of the frontal lobe and ACC. Implications for the potential clinical application of the herbal remedy to treat patients with frontal lobe disorders were discussed.