Research Article

Black Tea and Theaflavins Assist Healing of Indomethacin-Induced Gastric Ulceration in Mice by Antioxidative Action

Figure 1

Concentration-dependent healing capacities of (a) BT and (b) TF on the 3rd day after indomethacin-induced stomach ulceration in mice. Ulceration in the mice was induced by indomethacin (18 mg/kg, p. o.). The healing capacity was calculated from macroscopic damage scores (MDS), measured 4 h after the last dose of the test samples. The MDS in ulcerated untreated mice was taken as 100. The values are mean   S.E.M of three independent experiments, each with 5 mice/group. The IC50 values (concentration that produces 50% ulcer healing) of BT and TF (determined by Probit analysis) were significantly different ( ).
546560.fig.001a
(a)
546560.fig.001b
(b)