Table 1: Natural alternatives for reducing inflammation in autoimmune conditions.

AgentReferenceResult

Moutan cortex[19]Reduced concentration of TNF- , IL-1 and IL-6 in LPS-stimulated RAW264.7 cells
Moutan cortex[20]Increased production of IL-10 and a decrease in level of proinflammatory cytokines
Perillae Fructus[21]Suppressed IL-4 production, inhibiting IgE secretion; reduced IL-5 and IL-13; suppressed excess Th2 activity and rebalanced Th1/Th2
Atractylenolide I[22]Up-regulate TNF; down-regulate IL-1
Tibetan medicated-bath[23]Decreased IL-6 and TNF- levels
Opuntia humifusa Raf[24]Blocked expression of IL-6 from LPS-stimulated RAW264.7 cells
Total Flavonoids of Fructus Chorspondiatis[25]Inhibited NF- B signaling pathway
Artemisia annua L.[26]Inhibited IL-17A production; reduced mRNA expression of ROR t; reduced IL-6 production
Kummerowia striata (Thunb.) Schindl ethanol extract[27]Suppressed NF- B activation; up-regulated IL-10 and HO-1
Artemisia alba[28]Inhibited IL-1-induced NF- B and AP-1 activation
Ginger extract from Alpinia gallanga and Zingiber officinale[28]Reduced level of mRNA
Longicera japonica[28]Inhibited LPS-induced degradation of I- B and induction of NF- B p65, TNF- and inducible NO synthase (iNOS)
Phlebodium decumanum[28]Reduced TNF production; inhibited IL-6 production; increased release of TNF-R2 and IL-1 receptor agonist
Scandix austalis extracts[28]Inhibited IL-1-induced NF- B and AP-1 activation
Tripterygium wilfordii[28]Lowered the inflammatory response
Urtica dioica leaf extracts[28]Inhibited NF- B