Action Mechanisms of Du-Huo-Ji-Sheng-Tang on Cartilage Degradation in a Rabbit Model of Osteoarthritis

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left" rowspan="2">Treatments</td><td align="center" rowspan="2"><i>n</i></td><td align="center" colspan="2">10th week</td></tr><tr class="thead"><td align="center">VEGF</td><td align="center">HIF-1<i>α</i></td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">Normal group</td><td align="center">5</td><td align="center">0.55 ± 0.23**</td><td align="center">0.69 ± 0.17**</td></tr><tr><td align="left">Control group</td><td align="center">5</td><td align="center">125.01 ± 26.07</td><td align="center">160.35 ± 72.27</td></tr><tr><td align="left">DHJST group</td><td align="center">5</td><td align="center">20.34 ± 2.16**</td><td align="center">5.44 ± 2.36**</td></tr><tr><td align="left">OSA group</td><td align="center">5</td><td align="center">113.42 ± 42.32<sup>†</sup></td><td align="center">120.44 ± 81.12<sup>†</sup></td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td>Values as means ± SD.<br/><sup>†</sup><i>P </i> &gt; .05 compared with control group animals.<br/>
                **
                <i>P</i> &lt; .01 compared with control group animals.<br/></td></tr></table>

The influence of DHJST on HIF-1<i>α</i> mRNA and VEGF mRNA in the cartilage cells of rabbits at 10th week.

Evidence-Based Complementary and Alternative Medicine

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Table 3

Table 3: Action Mechanisms of Du-Huo-Ji-Sheng-Tang on Cartilage Degradation in a Rabbit Model of Osteoarthritis 