3,4-Di-O-Caffeoylquinic Acid Inhibits Angiotensin-II-Induced Vascular Smooth Muscle Cell Proliferation and Migration by Downregulating the JNK and PI3K/Akt Signaling Pathways
Figure 2
rVSMC proliferation.
(a) Concentration-dependent responsiveness
of Ang-II-induced rVSMC proliferation. (b)
3,4-di-O-caffeoylquinic acid dose-dependently
inhibited 100 nM Ang-II-induced proliferation.
and , significant difference versus samples
treated with Ang II alone. Each histogram represents the mean ± SE of three
separate experiments run in triplicate on four separate cultures.
