Herbal Medicine Containing Licorice May Be Contraindicated for a Patient with an HSD11B2 Mutation

Figure 1

DHPLC screening for a mutation in the HSD11B2 gene. Screening showed a small and large peak on the chromatogram of HSD11B2 exon 1, while controls showed a single peak. The small peak indicated heteroduplex DNA formation, suggesting the presence of a mutation in the patient’s HSD11B2 exon 1.