Original Article
Mechanism of Wound-Healing Activity of Hippophae rhamnoides L. Leaf Extract in Experimental Burns
Table 1
Effect of topical application of SBT lyophilized aqueous leaf extract on wound area contraction (mm2).
| Post wounding day | Burn control | SBT aqueous leaf extract | SSD | | | 2.5% (w/w) | 5.0% (w/w) | 7.5% (w/w) | 10.0% (w/w) |
| Day 0 | 176.83 ± 0.87 | 177.67 ± 1.26 | 178.33 ± 0.99 | 179.17 ± 0.60 | 177.33 ± 0.99 | 176.5 ± 1.80 | Day 4 | 138.50 ± 4.60 (22) | 124.50 ± 2.79 (30) | 113.17 ± 3.48* (37) | 121.33 ± 3.57* (32) | 133.00 ± 3.17 (25) | 128.83 ± 5.28 (27) | Day 8 | 90.83 ± 2.63 (49) | 71.67 ± 3.68* (60) | 50.33 ± 3.84* (71) | 63.33 ± 3.79*(65) | 79.00 ± 3.48 (55) | 72.00 ± 4.33* (59) |
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Values are mean ± SE; n = 6; Numbers in parenthesis indicate percentage of wound contraction.
*
P < .05 compared with burn control.
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