Mechanism of Wound-Healing Activity of Hippophae rhamnoides L. Leaf Extract in Experimental Burns

Table 3

Effect of topical application of SBT lyophilized aqueous leaf extract (5.0% w/w) for 7 days on the levels of antioxidants and lipid peroxide (in terms of MDA) in granulation tissue.

Parameters	Burn control	SBT leaf extract
Glutathione (μg mg^−1 protein)	1.68 ± 0.07	2.16 ± 0.09*
Vitamin C (μg mg^−1 protein)	2.46 ± 0.37	3.60 ± 0.27*
Superoxide dismutase (U mg^−1 protein)	1.25 ± 0.07	1.61 ± 0.06*
Catalase (U mg^−1 protein)	8.18 ± 0.35	10.03 ± 0.46*
Glutathione-S-transferase (U mg^−1 protein)	2.04 ± 0.08	2.45 ± 0.15*
MDA (nmol mg^−1 protein)	2.41 ± 0.12	1.79 ± 0.21*

Values are mean ± SE; n = 6.
* P < .05 compared with burn control.