A Valepotriate Fraction of Valeriana glechomifolia Shows Sedative and Anxiolytic Properties and Impairs Recognition But Not Aversive Memory in Mice
Figure 1
Open-field behavior and habituation in mice treated with a systemic administration of VF (1, 3 or 10 mg kg-1) of V. glechomifolia 30 min before the first open-field exploration session. Animals were left to freely explore the arena for 5 min day-1 during 2 days. Data are mean SEM. (a) Latency to start locomotion (s), (b) number of fecal pellets, (c) number of crossings and (d) number of rearings. n = 10 animals per group. , significant difference from the control group.
