Nordihydroguaiaretic Acid from Creosote Bush (Larrea tridentata) Mitigates 12-O-Tetradecanoylphorbol-13-Acetate-Induced Inflammatory and Oxidative Stress Responses of Tumor Promotion Cascade in Mouse Skin
Figure 2
Effect of NDGA on TPA induced (a) MPO activity, (b) edema formation, (c) CAT and (d) SOD activity in mouse skin from different treatment groups. Values are expressed as means ± SE (n = 6) of units of MPO/min/mg protein, cutaneous edema as mg/punch, catalase activity as nmol H2O2 consumed/min/mg protein and SOD activity as units/mg protein. Significant differences are indicated by ***P .001 when compared with control animals (Group I) and #P .05, ##P .01 and ###P .001 when compared with TPA-treated animals (Group II).
