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Evidence-Based Complementary and Alternative Medicine
Volume 2011 (2011), Article ID 745262, 7 pages
http://dx.doi.org/10.1155/2011/745262
Research Article

Quercetin and Bornyl Acetate Regulate T-Lymphocyte Subsets and INF-γ/IL-4 Ratio In Utero in Pregnant Mice

1College of Traditional Chinese Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China
2College of Animal Science and Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China

Received 25 April 2010; Revised 21 June 2010; Accepted 10 September 2010

Copyright © 2011 Xiaodan Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Chaouat, A. A. Meliani, J. Martal et al., “IL-10 prevents naturally occurring fetal loss in the CBA × DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-γ.,” Journal of Immunology, vol. 154, pp. 4261–4268, 1995. View at Google Scholar
  2. L. Krishnan, L. J. Guilbert, T. G. Wegmann, M. Belosevic, and T. R. Mosmann, “T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions: correlation with increased IFN-γ and TNF and reduced IL-10 production by placental cells,” Journal of Immunology, vol. 156, no. 2, pp. 653–662, 1996. View at Google Scholar · View at Scopus
  3. T. G. Wegmann, H. Lin, L. Guilbert, and T. R. Mosmann, “Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?” Immunology Today, vol. 14, no. 7, pp. 353–356, 1993. View at Google Scholar · View at Scopus
  4. M.-P. Piccinni, D. Bani, L. Beloni et al., “Relaxin favors the development of activated human T cells into Th1-like effectors,” European Journal of Immunology, vol. 29, no. 7, pp. 2241–2247, 1999. View at Publisher · View at Google Scholar · View at Scopus
  5. D. Lin, M. A. Smith, C. Champagne, J. Elter, J. Beck, and S. Offenbacher, “Porphyromonas gingivalis infection during pregnancy increases maternal tumor necrosis factor alpha, suppresses maternal interleukin-10, and enhances fetal growth restriction and resorption in mice,” Infection and Immunity, vol. 71, no. 9, pp. 5156–5162, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. E. G. Olivares, R. Muńoz, G. Tejerizo, M. J. Montes, F. Gómez-Molina, and A. C. Abadía-Molina, “Decidual lymphocytes of human spontaneous abortions induce apoptosis but not necrosis in JEG-3 extravillous trophoblast cells,” Biology of Reproduction, vol. 67, no. 4, pp. 1211–1217, 2002. View at Google Scholar · View at Scopus
  7. S. Mandal, B. Hazra, R. Sarkar, S. Biswas, and N. Mandal, “Assessment of the antioxidant and reactive oxygen species scavenging activity of methanolic extract of Caesalpinia crista leaf,” Evidence-Based Complementary and Alternative Medicine. In press.
  8. R. Salazar-Aranda, L. A. Pérez-López, J. López-Arroyo, B. A. Alanís-Garza, and N. Waksman de Torres, “Antimicrobial and antioxidant activities of plants from Northeast of Mexico,” Evidence-Based Complementary and Alternative Medicine. In press.
  9. T. R. Calvo, C. R. Cardoso, A. C. da Silva Moura et al., “Mutagenic activity of Indigofera truxillensis and I. suffruticosa aerial Parts,” Evidence-Based Complementary and Alternative Medicine. In press.
  10. N. K. Upadhyay, R. Kumar, M. S. Siddiqui, and A. Gupta, “Mechanism of wound-healing activity of Hippophae rhamnoides L. leaf extract in experimental burns,” Evidence-Based Complementary and Alternative Medicine. In press.
  11. M. F. Mouat, K. Kolli, R. Orlando, J. L. Hargrove, and A. Grider, “The effects of quercetin on SW480 human colon carcinoma cells: a proteomic study,” Nutrition Journal, vol. 4, p. 11, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. T. Ou, C. Wang, G. Hung, C. Wu, and H. Lee, “Aqueous extract of Shi-Liu-Wei-Liu-Qi-Yin Induces G2/M phase arrest and apoptosis in human bladder carcinoma cells via Fas and mitochondrial pathway,” Evidence-Based Complementary and Alternative Medicine. In press.
  13. J. L. Capodice, D. L. Bemis, R. Buttyan, S. A. Kaplan, and A. E. Katz, “Complementary and alternative medicine for chronic prostatitis/chronic pelvic pain syndrome,” Evidence-based Complementary and Alternative Medicine, vol. 2, no. 4, pp. 495–501, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. G. Fredriksson, H. Kindahl, and G. Stabenfeldt, “Endotoxin-induced and prostaglandin-mediated effects on corpus luteum function in the mare,” Theriogenology, vol. 25, no. 2, pp. 309–316, 1986. View at Google Scholar · View at Scopus
  15. S. N. Giri, P. Emau, J. S. Cullor et al., “Effects of endotoxin infusion on circulating levels of eicosanoids, progesterone, cortisol, glucose and lactic acid, and abortion in pregnant cows,” Veterinary Microbiology, vol. 21, no. 3, pp. 211–231, 1990. View at Publisher · View at Google Scholar · View at Scopus
  16. B. Beutler, D. Greenwald, J. D. Hulmes et al., “Identity of tumour necrosis factor and the macrophage-secreted factor cachectin,” Nature, vol. 316, no. 6028, pp. 552–554, 1985. View at Google Scholar · View at Scopus
  17. G. E. Gifford and M.-L. Lohmann-Matthes, “Gamma interferon priming of mouse and human macrophages for induction of tumor necrosis factor production by bacterial lipopolysaccharide,” Journal of the National Cancer Institute, vol. 78, no. 1, pp. 121–124, 1987. View at Google Scholar · View at Scopus
  18. D. K. Blanchard, J. Y. Djeu, and T. W. Klein, “Interferon-γ induction by lipopolysaccharide: dependence on interleukin 2 and macrophages,” Journal of Immunology, vol. 136, no. 3, pp. 963–970, 1986. View at Google Scholar · View at Scopus
  19. X.-H. Zhong, Z.-X. Zhou, T.-S. Li, E.-Q. Wang, W.-Y. Shi, and S.-M. Chu, “Anti-abortive effect of Radix scutellariae and Rhizoma atractylodis in mice,” American Journal of Chinese Medicine, vol. 30, no. 1, pp. 109–117, 2002. View at Publisher · View at Google Scholar · View at Scopus
  20. X.-H. Zhong, W.-Y. Shi, A.-T. Ma et al., “Effects of Radix scutellariae and Rhizoma atractylodis on LPS-induced abortion and the uterine IL-10 contents in mice,” American Journal of Chinese Medicine, vol. 36, no. 1, pp. 141–148, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. P. F. Terranova and V. Montgomery Rice, “Review: cytokine involvement in ovarian processes,” American Journal of Reproductive Immunology, vol. 37, no. 1, pp. 50–63, 1997. View at Google Scholar · View at Scopus
  22. D. G. Ogando, D. Paz, M. Cella, and A. M. Franchi, “The fundamental role of increased production of nitric oxide in lipopolysaccharide-induced embryonic resorption in mice,” Reproduction, vol. 125, no. 1, pp. 95–110, 2003. View at Google Scholar · View at Scopus
  23. R. Lin, J. Liu, and W. Gan, “Protection of vascular endothelial cells from TNF-alpha induced injury by quercetin,” Zhong Yao Cai (Chinese Herbal Medicine), vol. 27, no. 8, pp. 597–599, 2004. View at Google Scholar
  24. K. R. Manjeet and B. Ghosh, “Quercetin inhibits LPS-induced nitric oxide and tumor necrosis factor-α production in murine macrophages,” International Journal of Immunopharmacology, vol. 21, no. 7, pp. 435–443, 1999. View at Publisher · View at Google Scholar · View at Scopus
  25. Z. -Q. Liang, Y. Zhu, Z. -L. Gu, Q. Lu, and P. -S. Fan, “Effects of quercetin on platelet-endothelial cell adhesion and their expression of adhesion molecules,” Acta Pharmaceutica Sinica, vol. 38, no. 8, pp. 574–577, 2003. View at Google Scholar
  26. J. S. Zhu, Y. M. Gao, and H. L. Wang, “Study on the changes of T-lymphocytes and subsets in deciduas with recurrent spontaneous abortion,” Maternal and Child Health Care of China, vol. 21, no. 10, pp. 1405–1406, 2006. View at Google Scholar
  27. M. Michel, J. Underwood, D. A. Clark, J. F. Mowbray, and R. W. Beard, “Histologic and immunologic study of uterine biopsy tissue of women with incipient abortion,” American Journal of Obstetrics and Gynecology, vol. 161, no. 2, pp. 409–414, 1989. View at Google Scholar · View at Scopus
  28. O. Petrović, L. Gudelj, G. Rube, H. Haller, A. E. Beer, and D. Rukavina, “Decidual-trophoblast interactions: decidual lymphoid cell function in normal, anembryonic, missed abortion and ectopic human pregnancy,” Journal of Reproductive Immunology, vol. 26, no. 3, pp. 217–231, 1994. View at Publisher · View at Google Scholar · View at Scopus
  29. N. Vassiliadou and J. N. Bulmer, “Characterization of endometrial T lymphocyte subpopulations in spontaneous early pregnancy loss,” Human Reproduction, vol. 13, no. 1, pp. 44–47, 1998. View at Publisher · View at Google Scholar · View at Scopus
  30. J. A. Hill, K. Polgar, B. L. Harlow, and D. J. Anderson, “Evidence of embryo- and trophoblast-toxic cellular immune response(s) in women with recurrent spontaneous abortion,” American Journal of Obstetrics and Gynecology, vol. 166, no. 4, pp. 1044–1052, 1992. View at Google Scholar · View at Scopus
  31. J. A. Hill, K. Polgar, and D. J. Anderson, “T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion,” Journal of the American Medical Association, vol. 273, no. 24, pp. 1933–1936, 1995. View at Google Scholar · View at Scopus
  32. C. Cui, X. J. Bai, S. W. Liu, Y. X. Jin, and J. D. Liu, “Changes of decidual lymphocytic function from patients with unexplained spontaneous early abortion,” Journal of Bethune Military Medical College, vol. 2, no. 2, pp. 70–72, 2004. View at Google Scholar
  33. M. Marzi, A. Vigano, D. Trabattoni et al., “Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy,” Clinical and Experimental Immunology, vol. 106, no. 1, pp. 127–133, 1996. View at Google Scholar · View at Scopus
  34. R. Raghupathy, M. Makhseed, R. Azizieh, A. Omu, M. Gupta, and R. Farhat, “Cytokine production by maternal lymphocytes during normal human pregnancy and in unexplained recurrent spontaneous abortion,” Human Reproduction, vol. 15, no. 3, pp. 713–718, 2000. View at Google Scholar · View at Scopus
  35. E. K. Haddad, A. J. Duclos, E. Antecka, W. S. Lapp, and M. G. Baines, “Role of interferon-γ in the priming of decidual macrophages for nitric oxide production and early pregnancy loss,” Cellular Immunology, vol. 181, no. 1, pp. 68–75, 1997. View at Publisher · View at Google Scholar · View at Scopus
  36. S. L. Klein, B. H. Bird, and G. E. Glass, “Sex differences in immune responses and viral shedding following Seoul virus infection in Norway rats,” American Journal of Tropical Medicine and Hygiene, vol. 65, no. 1, pp. 57–63, 2001. View at Google Scholar · View at Scopus
  37. G. B. Dealtry, M. K. O'Farrell, and N. Fernandez, “The Th2 cytokine environment of the placenta,” International Archives of Allergy and Immunology, vol. 123, no. 2, pp. 107–119, 2000. View at Google Scholar · View at Scopus