Evaluation of In Vitro Uterotonic Activities of Fruit Extracts of Ficus asperifolia in Rats

Figure 4

Schematic diagram of proposed mechanism of F. asperifolia-induced contraction in estrogen-treated uterine muscle. For detailed description, see Discussion section. FA: Ficus asperifolia; H1: type 1 histamine receptor; OTR: oxytocin receptor; M2: type 2 muscarinic receptor; G: protein G; PLC: phospholipase C; Pg: prostaglandin; PIP2: phosphatidylinositol 4,5 biphosphate; IP3: inositol 1,4,5 triphosphate.