Addition of Fructooligosaccharides and Dried Plum to Soy-Based Diets Reverses Bone Loss in the Ovariectomized Rat

Table 3

Effects of ovariectomy (Ovx) and various dietary treatments on histomorphometric parameters of the left proximal tibia.

Parameters	Sham-casein	Ovx + casein	Ovx + soy	Ovx + soy + plum	Ovx + soy + FOS	Ovx + soy + plum + FOS
BV/TV (%)	11.9 ± 1.9^a	8.1 ± 1.9^a,b	6.7 ± 1.9^a,b	5.2 ± 1.9^b	8.3 ± 1.9^a,b	9.9 ± 1.9^a,b
Tb Th (μm)	46 ± 5^c	63 ± 5^a,b	58 ± 5^a,b,c	53 ± 5^b,c	61 ± 5^a,b	69 ± 5^a
Tb N (n)	2.46 ± 0.27^a	1.09 ± 0.27^b	1.19 ± 0.27^b	0.99 ± 0.27^b	1.26 ± 0.27^b	1.42 ± 0.27^b
Tb Sp (μm)	441 ± 198^b	1359 ± 198^a	1032 ± 198^a	1125 ± 198^a	959 ± 198^a,b	942 ± 198^a,b
MS/BS (%)	2.2 ± 2.0^b	10.2 ± 2.0^a	10.1 ± 2.0^a	8.9 ± 2.0^a	12.1 ± 2.0^a	6.5 ± 2.0^ab

Values are mean ± SE; 𝑛 = 6. Within a row, values that do not share the same superscript letters are significantly (𝑃<.05) different from each other. BV/TV = bone volume as percentage of tissue volume; Tb N = trabecular number.