Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study
Figure 4
Akt-related pathway activation in the presence or absence of STS (or Tan IIA) in epirubicin-treated BT-20 breast cancer cells for 24 h. (a) Representative results of Western blotting showing changes in the levels of Akt, phospho-Akt, JNK, phospho-JNK, P38, phospho-p38, MAPK, and phospho-MAPK in BT-20 cells treated with STS and/or 1 μg/mL epirubicin. (b) Representative results of Western blotting showing changes in the levels of Akt, phospho-Akt, JNK, phospho-JNK, P38, phospho-p38, MAPK, and phospho-MAPK in BT-20 cells treated with Tan IIA and/or 1 μg/mL epirubicin.
