San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways

<table>Effects of SHXT on myocardial infarct size and plasma levels of CK-MB, LDH and troponin I in rat hearts subjected to I/R. (a) Bar graphs show area at risk of infarction indexed to total left ventricle (AAR/Total LV), infarcted area indexed to area at risk of (INF/AAR), and infarcted area indexed to total left ventricle (INF/Total LV). (b)–(d) Effects of pretreatment with SHXT on plasma levels of cardiac enzymes. Each value represents the mean ± SEM of six rats. <svg height="13.95" id="M15" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 65.150002 13.95" width="65.150002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus sham group; <svg height="14.3125" id="M16" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.162498 14.3125" width="58.162498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus vehicle-treated rats. ANOVA followed by Dunnett’s test.</table>

Evidence-Based Complementary and Alternative Medicine

fig1

Figure 1

Figure 1: San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways 