Inhibitory Effect of Polyphenol-Rich Fraction from the Bark of Acacia mearnsii on Itching Associated with Allergic Dermatitis

Figure 1

Analysis of spontaneous itching behaviour. HR-1 mice were given free access to a normal diet (control group), HR-AD diet (AD group), HR-AD diet with 1.5% PrA, or HR-AD diet with 3.0% PrA for 6 weeks. The spontaneous itching behaviour of mice was observed at 4 weeks (a)–(c) and 6 weeks (d)–(f) after the administration, and the frequency of spontaneous itching behaviour per hour was calculated. Data represent the mean ± SD for 8 mice. Tukey’s test: **𝑃<0.01 and ***𝑃<0.001 versus control group, ^##𝑃<0.01 and ^###𝑃<0.001 versus AD group.

(a)

(b)

(c)

(d)

(e)

(f)