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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 127043, 10 pages
http://dx.doi.org/10.1155/2012/127043
Research Article

Interaction between Red Yeast Rice and CYP450 Enzymes/P-Glycoprotein and Its Implication for the Clinical Pharmacokinetics of Lovastatin

1School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan
2School of Pharmacy, Taipei Medical University, Taipei 100, Taiwan
3Department of Internal Medicine, Hospital and College of Medicine, National Taiwan University, Taipei 100, Taiwan

Received 29 May 2012; Revised 13 September 2012; Accepted 3 October 2012

Academic Editor: Alfredo Vannacci

Copyright © 2012 Chia-Hao Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Chia-Hao Chen, Jyh-Chin Yang, Yow-Shieng Uang, and Chun-Jung Lin, “Improved dissolution rate and oral bioavailability of lovastatin in red yea st rice products,” International Journal of Pharmaceutics, vol. 444, no. 1-2, pp. 18–24, 2013. View at Publisher · View at Google Scholar
  • Mark Houston, “The role of nutrition and nutritional supplements in the treatment of dyslipidemia,” Clinical Lipidology, vol. 9, no. 3, pp. 333–354, 2014. View at Publisher · View at Google Scholar
  • Manthena V.S. Varma, Jian Lin, Yi-An Bi, Emi Kimoto, and A. David Rodrigues, “Quantitative rationalization of gemfibrozil drug interactions: Consideration of transporters-enzyme interplay and the role of circulating metabolite gemfibrozil 1-O-b-Glucuronide,” Drug Metabolism and Disposition, vol. 43, no. 7, pp. 1108–1118, 2015. View at Publisher · View at Google Scholar
  • Andrew Stolbach, Karolina Paziana, Harry Heverling, and Paul Pham, “A Review of the Toxicity of HIV Medications II: Interactions with Drugs and Complementary and Alternative Medicine Products,” Journal of Medical Toxicology, vol. 11, no. 3, pp. 326–341, 2015. View at Publisher · View at Google Scholar
  • Anna Woodbury, Stephen Neal Soong, David Fishman, and Paul S. García, “Complementary and alternative medicine therapies for the anesthesiologist and pain practitioner: a narrative review,” Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2015. View at Publisher · View at Google Scholar
  • Qigang Guan, Wei Chen, and Xianming Hu, “Development of lovastatin-loaded poly(lactic acid) microspheres for sustained oral delivery: in vitro and ex vivo evaluation,” Drug Design Development And Therapy, vol. 9, pp. 791–798, 2015. View at Publisher · View at Google Scholar
  • Gemma Leone, Simone Pepi, Stefania Lamponi, Gabriella Tamasi, Agnese Magnani, Marco Consumi, Claudia Bonechi, Alessandro Donati, and Claudio Rossi, “New formulations to enhance lovastatin release from red yeast rice (RYR),” Journal of Drug Delivery Science and Technology, vol. 36, pp. 110–119, 2016. View at Publisher · View at Google Scholar
  • Elena Yu. Enioutina, Emma R. Salis, Kathleen M. Job, Michael I. Gubarev, Lubov V. Krepkova, and Catherine M. T. Sherwin, “Herbal Medicines: challenges in the modern world. Part 5. status and current directions of complementary and alternative herbal medicine worldwide,” Expert Review of Clinical Pharmacology, pp. 1–12, 2016. View at Publisher · View at Google Scholar
  • Christelle Philibert, Virginie Bres, Marie-Jos?phe Jean-Pastor, Claire Guy, B?n?dicte Lebrun-Vignes, Perrine Robin, V?ronique Pinzani, and Dominique Hillaire-Buys, “Atteintes musculaires et levure de riz rouge?: analyse des donn?es de la base nationale de pharmacovigilance et revue de la litt?rature,” Th?rapie, 2016. View at Publisher · View at Google Scholar
  • Amirhossein Sahebkar, Maria-Corina Serban, Anna Gluba-Brzózka, Dimitri P. Mikhailidis, Arrigo F. Cicero, Jacek Rysz, and Maciej Banach, “Lipid-modifying effects of nutraceuticals: An evidence-based approach,” Nutrition, vol. 32, no. 11-12, pp. 1179–1192, 2016. View at Publisher · View at Google Scholar