Research Article

Involvement of Heme Oxygenase-1 Induction in the Cytoprotective and Immunomodulatory Activities of Viola patrinii in Murine Hippocampal and Microglia Cells

Figure 5

Effects of NNMBS275 on HO-1 expression in BV2 microglia (a and b) and HT22 (c and d). BV2 microglia and HT22 cells were incubated for 12 h with indicated concentrations of NNMBS275 (a and c) and periods with 200 μg/mL of NNMBS275 (b and d). The HO-1 inducer CoPP, increased HO-1 expression at 20 μM (a and c). Western blot analysis for HO-1 expression was performed as described in Section 2, and representative blots of 3 independent experiments are shown. Data represent the mean values of 3 experiments ± S.D. * compared to the control group.
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(a) BV2 microglia
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(b) BV2 microglia
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(c) HT22 cells
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(d) HT22 cells