Efficacy and Safety of Human Placental Extract Solution on Fatigue: A Double-Blind, Randomized, Placebo-Controlled Study

Table 2

Demographic information and characteristics of the subjects.

	Demographic information		Group 1	Group 2	Placebo group	P value
			𝑁=101	𝑁=102	𝑁=96
Sex	Male	n (%)	13 (12.87)	22 (21.57)	13 (13.54)	0.1729^†
	Female	n (%)	88 (87.13)	80 (78.43)	83 (86.46)
Fertility	No	n (%)	24 (27.27)	16 (20.00)	16 (19.28)	0.3796^†
	Yes	n (%)	64 (72.73)	64 (80.00)	67 (80.72)
Age	Age (years)	Mean ± SD	41.20 ± 10.89	40.53 ± 11.23	39.97 ± 11.94	0.7486^$
	18–29 years	n (%)	14 (13.86)	15 (14.71)	21 (21.88)	0.5497^†
	30–39 years	n (%)	30 (29.70)	41 (40.20)	30 (31.25)
	40–49 years	n (%)	33 (32.67)	25 (24.51)	24 (25.00)
	50–59 years	n (%)	19 (18.81)	14 (13.73)	15 (15.63)
	60–75 years	n (%)	5 (4.95)	7 (6.86)	6 (6.25)
	Anxiety (HADS)	Mean ± SD	6.75 ± 2.59	5.81 ± 2.36	5.97 ± 2.55	0.0178^$
	Depression (HADS)	Mean ± SD	6.74 ± 2.43	6.60 ± 2.41	6.69 ± 2.40	0.9114^$
	Height (cm)	Mean ± SD	159.70 ± 6.50	161.20 ± 6.79	161.30 ± 7.10	0.1759^$
	Weight (kg)	Mean ± SD	57.09 ± 9.19	57.73 ± 9.02	58.55 ± 9.54	0.5410^$
	Heart rate (beat/minute)	Mean ± SD	73.94 ± 8.39	74.67 ± 8.76	74.69 ± 8.18	0.7759^$
	Systolic BP (mmHg)	Mean ± SD	117.64 ± 13.64	115.44 ± 12.46	119.10 ± 13.26	0.1424^$
	Diastolic BP (mmHg)	Mean ± SD	74.33 ± 9.81	72.78 ± 8.78	75.07 ± 9.46	0.2135^$
Alcohol	No	n (%)	81 (80.20)	83 (81.37)	77 (80.21)	0.9710^†
consumption	Yes	n (%)	20 (19.80)	19 (18.63)	19 (19.79)
Serious life	No	n (%)	98 (97.03)	95 (93.14)	94 (97.92)	0.2544^‡
events	Yes	n (%)	3 (2.97)	7 (6.86)	2 (2.08)

^$ANOVA, ^†Chi-square test, ^‡Fisher’s exact test.