Analgesic and Anti-Inflammatory Activities of Methanol Extract of Cissus repens in Mice

Table 2

Effect of CR_MeOH and indomethacin on COX concentrations in mouse paw edema.

Groups	COX-1; (U/mL/mg protein)	COX-2; (U/mL/mg protein)
Carr	133.588 ± 5.583	207.273 ± 9.984
Carr + Indomethacin	90.850 ± 2.963***	135.669 ±7.489***
Carr + CRMeOH (20 mg/kg)	133.188 ± 6.656	162.505 ± 12.750
Carr + CRMeOH (100 mg/kg)	132.383 ± 7.511	148.923 ± 14.681*
Carr + CRMeOH (500 mg/kg)	129.140 ± 5.214	134.936 ± 9.918***

Each value represents the mean ± S.E.M. (n = 8). *P < 0.05 and ***P < 0.001 as compared with the λ-carrageenan (Carr) group (one-way ANOVA followed by Scheffe’s multiple range test).